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In conclusion, and in line with its 2 h half-life in patients, in vitro studies should be carried out thoroughly considering ascorbic acid chemistry with recommended experimental conditions such as avoiding catalytic metals in culture media, using a dosing per cell metric scheme and a 2 h treatment with a media refresh step [13, 126, 156]

Secondary effects from IGF-1 therapy were reported after administration of doses higher than 6080 g/kg/day

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Regulation of endoplasmic reticulum turnover by selective autophagy

A pilot randomized clinical trial: Oral miltefosine and pentavalent antimonials associated with pentoxifylline for the treatment of American tegumentary leishmaniasis