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(Neelakantan et al., 2018) observed that systemic administration of NNMTi to mice with diet-induced obesity markedly attenuated WAT mass and body weight, diminished adipocyte volume, and reduced plasma TC levels
Following the loading phase, maintenance injections are given every two to three months for life, as pernicious anaemia is a chronic condition requiring ongoing treatment
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The animal data suggest lean mass is preserved, but human body composition data is lacking
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