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It serves as a key component for cellular energy production and metabolism

Given that the inhibition of the UPS activity is associated with the accumulation of A42 oligomers and misfolded tau, enhancing UPS function has been put forward as a promising therapeutic strategy for AD

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If confirmed as HHS director, Kennedy would retain the arrangement only in cases that do not directly affect the federal government

The accumulation of senescent cells in different organs is a precursor of fibrosis development, neurological disorders, or chronic diseases and the rational to develop specific therapies targeting senescent cells has emerged as a promising therapeutic way 2,3,4