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Analysis of the double mutants lacking glutathione or thioredoxin suggested that theses antioxidant molecules are not responsible for compensating in vivo the absence of CgCta1.10 To date, the role of CgCta1 as a virulence factor has not been established as in other pathogenic fungi.8 Superoxide dismutases SODs are metalloenzymes that catalyze the dismutation of O2 into H2O2 and oxygen

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Ghibelli L, Fanelli C, Rotilio G, Lafavia E, Coppola S, et al

Antioxidants inhibit low density lipoprotein oxidation less at lysosomal pH: a possible explanation as to why the clinical trials of antioxidants might have failed