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This review aims to highlight the central role of OS in the pathophysiology of ALS, specifically focusing on the KEAP1-NRF2 system and its alteration in ALS, while discussing the potential applications of NRF2 activators in ALS therapy

doi: 10.1158/0008-5472.CAN-06-4699

Glutathione has been considered as a wonder drug for the treatment of hyperpigmentation

Taniguchi N., Higashi T., Sakamoto Y., Meister A., editors

introduction of two random mutations of Y444A and G484A to D433N resulted in up to 50-fold increase in catalytic efficiency for GL-7-ACA substrate (Yamada et al., 2008)
