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Interestingly, SHARP interacts with RBM15 in a SPOC-dependent manner (Fig

The more consequential development for DCT neurology market growth is the FDA and EMA's increasing receptivity to digital outcome assessments (DOAs) as primary endpoints in pivotal rare disease submissions a position reflected in growing scientific advice correspondence and in the number of Phase III neurology programs formally designating DOA instruments as primary or key secondary endpoints

Solubility Parameter Approach The functional group contribution method was used to determine the Hansen solubility parameter for the drug and carriers [5]

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