nac or reduced glutathione The Antioxidant Role of and N-Acetyl-Cysteine Supplements and Exercise-Induced Oxidative Stress N-acetylcysteine infusion alters blood redox
Description
2016;354:aad6872

Furthermore, administration of MSG induced oxidative stress in adult Wistar rats and causes some undesirable effects on the liver at higher doses (45)

Republic of Korea Patent Application

The pineal gland produces approximately 0.5 mg of melatonin per day, depending on age, lifestyle, physical exercise, and use of medications, and its production declines with age

Both are generally considered safe for long-term use at standard supplementation levels
