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Pediatr Drugs

Global, regional, and national burden of neurological disorders, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016

Thus, excessive CB1 activation with exogenous THC may lead to NMDAR hypofunction which in turn downregulates genes involved in synthesis, recycling and utilization of GSH in developing neurons, promoting oxidative stress

Children: As directed by a healthcare professional

The large, dimeric enzyme operates through a FAD cofactor and two essential cysteines, one of which is proximal to the glutathione disulfide docking site and the other to the FAD cofactor [129]
