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When our body is optimising fat as fuel (lipogenesis) the bouncer at the door is Carnitine palmitoyltransferase which allows lipids to enter the cells to where they will enter the mitochondria and convert down the electron transport chain into energy

The resultant glycerol-3-phosphate is then converted to the glycolytic intermediate, dihydroxyacetone phosphate (DHAP), via the action of cytosolic glycerol-3-phosphate dehydrogenase (GPD1), and is utilized for glucose synthesis via the gluconeogenesis pathway

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Crosstalk between PTEN/PI3K/Akt signalling and DNA damage in the oocyte: implications for primordial follicle activation, oocyte quality and ageing