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They advocate for a treatment approach that is: Symptom-led : Recognising that many patients become symptomatic well before their next scheduled dose, meaning they are being under-treated

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Testosterone production in men occurs mainly in specialized cells in the testes called Leydig cells and is regulated by a signaling network known as the hypothalamic-pituitary-testicular axis: gonadotropin-releasing hormone (GnRH) from the brains hypothalamus triggers the pituitary gland to secrete luteinizing hormone (LH) into circulation

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