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HIF-1 is the key transcriptional factor that masterfully regulates endothelial cell biology and angiogenesis, particularly under hypoxic and oxidative stress conditions, by upregulating pro-angiogenic factors, such as VEGF 33

Further decontamination with irrigation solutions can be done, but treatment with antidote is the first priority and should not be delayed

Anti-carcinoembryonic antigen (CEA) diabody for rapid tumor targeting and imaging

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DOI: 10.1016/j.cmet.2020.09.007 Lenkiewicz, E., Malasi, S., Hogenson, T.L., Flores, L.F., Barham, W., Phillips, W.J., Roesler, A.S., Chambers, K.R., Rajbhandari, N., Hayashi, A., Antal, C.E., Downes, M., Grandgenett, P.M., Hollingsworth, M.A., Cridebring, D., Xiong, Y., Lee, J.H., Ye, Z., Yan, H., Hernandez, M.C., Leiting, J.L., Evans, R.M., Ordog, T., Truty, M.J., Borad, M.J., Reya, T., Von Hoff, D.D., Fernandez-Zapico, M.E., Barrett, M.T
