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If so, what has been your experience and changes

reported that glioma cells carrying the EGFRvIII mutation show an overactivation of mTOR, being less responsive to the anti-tumor effect of dacomitinib [319]

10.1158/2159-8290.CD-17-0741 313 ReckM.SchenkerM.LeeK

Therefore, ethical approval were not required

Nevertheless, McKillop, et al

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