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In contrast, under stressed conditions, certain stress-sensing residues in Keap1 are oxidized, resulting in its conformational changes, inactivation and ultimately its dissociation from Keap1-Nrf2 complex allowing Nrf2 to escape degradation [21]

Furthermore, there are many compounds, including atractylenolide III (Zhong et al., 2022), asperuloside (Tan and Zheng, 2018), acteoside (Zhou et al., 2018), bruceine D (Zhang et al., 2017), baicalin (Yao et al., 2016), carnosic acid (Yang et al., 2017), D-pinitol (Lin et al., 2021), epoxymicheliolide (Yang et al., 2020), galangin (Sangaraju et al., 2019), 6-gingerol (Socca et al., 2014), imperatorin (Luo and Luo, 2021), lycopene (Tekeli et al., 2018

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