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Both intermittent dosing schedules (injections on specific days) and continuous daily administration showed benefits, suggesting some flexibility in protocol design

According to the literature, the autosomal recessive inheritance pattern is generally associated with a more severe clinical phenotype compared to autosomal dominant cases [38]

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For example, individuals with liver issues might benefit from specific detoxification protocols

Long-term dosing studies have also been conducted to evaluate tissue tolerance and inflammation markers, suggesting a favorable profile in terms of local joint impact and systemic safety