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Description
"Acetylation of Foxo1 alters its DNA-binding ability and sensitivity to phosphorylation"

Without adequate B12, the body produces fewer red blood cells and those that are produced may be abnormally large (megaloblastic)leading to anaemia and reduced oxygen delivery to tissues

Archived from the original on April 13, 2019

("BCE")

The study found that while low to moderate doses (2.5-250 g) provided some benefit, daily doses of around 500 g or more were required to restore healthy B12 levels
