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Key residues and conformation switches are labeled within the panel

Starting Doses Conservative protocols begin at 0.2-0.25 mg daily, allowing assessment of individual response before increasing dose

Functional impairment in aged MuSCs is accompanied by a shift in transcriptional programs, with increased expression of activation markers such as FOS , JUN , and EGR1 and reduced expression of quiescence-associated genes including CALCR and FOXO3