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10.1016/j.cmet.2017.10.006 [DOI] [PMC free article] [PubMed] [Google Scholar] 76.van de Donk N, Richardson PG, Malavasi F

Cartilage structure and limited repair capacity Avascular tissue challenges: Articular cartilage (covering joint surfaces) completely lacks blood vessels, nerves, and lymphatics

To our knowledge, dogs with naturally occurring IVD degeneration have not been used, even though it is recognized that CD dog breeds are a suitable animal model of spontaneous IVD degeneration [9, 13]

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