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10.1016/j.cmet.2017.10.006 [DOI] [PMC free article] [PubMed] [Google Scholar] 76.van de Donk N, Richardson PG, Malavasi F

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Cartilage structure and limited repair capacity Avascular tissue challenges: Articular cartilage (covering joint surfaces) completely lacks blood vessels, nerves, and lymphatics

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To our knowledge, dogs with naturally occurring IVD degeneration have not been used, even though it is recognized that CD dog breeds are a suitable animal model of spontaneous IVD degeneration [9, 13]

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