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The short answer is Until you are satisfied with improvements in communication and the treatment no longer seems to be helping. Another useful response is, Consider discontinuing mB12 when stimming becomes more disruptive than language acquisition. I find it peculiar that parents pose this question at all

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Gramer G, Hoffmann GF (2020) Vitamin B12 deficiency in newborns and their mothersnovel approaches to early detection, treatment and prevention of a global health issue

International Journal of Clinical Pharmacy 2013;35(6):12956

Mitochondria bound to lipid droplets have unique bioenergetics, composition, and dynamics that support lipid droplet expansion