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Horwitz EM, Le Blanc K, Dominici M, Mueller I, Slaper-Cortenbach I, Marini FC, et al

Chem Res Toxicol 2009;22:699707 [DOI] [PMC free article] [PubMed] [Google Scholar] 30.Tanaka R, Ishima Y, Maeda H, Kodama A, Nagao S, Watanabe H, Chuang VT, Otagiri M, Maruyama T.Albumin fusion prolongs the antioxidant and anti-inflammatory activities of thioredoxin in mice with acetaminophen-induced hepatitis

however, this does not involve -arrestin2 or NEDD4 (which are critical for agonist-induced ubiquitination), but requires a transmembrane RING-finger E3 ligase, MARCH2 (Membrane-associated RING-CH2) [102]

Tyr212 is located on a loop preceding 3 containing Glu217 and Lys231 forming the salt bridge in the tetramer (Fig

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