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Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation

NOTCH1/HES1 upregulation in GSCs drives invasion and recurrence [32]

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Ginsenoside Rc, the main active ingredient isolated from ginseng, increases the deacetylase activity of SIRT6, thereby decreasing the level of acetylated NRF2 and increasing the stability of NRF2, which in turn attenuates hepatocellular injury and oxidative stress in alcoholic liver disease [79]

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