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Chronodisruption: effects on reproduction, transgenerational health of offspring and epigenome

In this issue of the JCI, Nagasaki and colleagues demonstrate a role for 15LO1 in controlling redox balance and epithelial homeostasis in T2-high asthma by metabolizing AA that is esterified to membrane phospholipids

The Orbitrap Astral was operated in data-independent acquisition (DIA) mode, with MS1 scans acquired in the Orbitrap at a resolution of 240,000, with a maximum injection time of 5 ms over a range of 380980 m/z

doi: 10.1073/pnas.1318596110

With age, the natural levels of glutathione in the body gradually reduce