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Microbial fermentation yields adenosylcobalamin, which is then converted to cyanocobalamin by the addition of potassium cyanide or thiocyanate in the presence of sodium nitrite and heat

It has been used in ulcerative colitis trials and has shown potential in counteracting the leaky gut syndrome and free radical scavenging activity in various tissues

Traumatic brain injury increases -amyloid peptide 142 in cerebrospinal fluid

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A Vitamin B12 deficiency can potentially cause severe and irreversible damage, especially to the brain and nervous system
