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Mammalian organisms, including humans, have evolved the ability to eliminate HTL and one such mechanism involves paraoxonase 1 (PON1), a high-density lipid (HDL) associated protein

[DOI] [PMC free article] [PubMed] [Google Scholar] 74.Girgis H, Palmier B, Croci N, Soustrat M, Plotkine M, Marchand-Leroux C

The observed alterations in energy and lipid metabolism present promising therapeutic avenues for alleviating symptoms in these patient populations

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( C ) cyto-GsBP2 accelerates G binding to Gs after GPCR signal termination, whereas the GsBP2 W11A mutant has no effect