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Researchers consulting this page should weight the evidence base accordingly

A safe serum range is 200350 ng/L, depending on age and clinical condition

When youre vitamin B12 deficient, it can lead to various symptoms including fatigue, weakness, shortness of breath, heart palpitations, and more

Notable recent developments include the first preclinical study demonstrating NNMT inhibition improves cardiac function and reduces fibrosis in a heart failure model (Li et al., 2025), a comprehensive review of NNMT as a therapeutic target for neurodegenerative disorders (Liu et al., 2025), and emerging evidence that NNMT inhibition counteracts tubular senescence and fibrosis in chronic kidney disease