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In the DESIRES multicenter RCT, fifty-six patients in Japan with scleroderma and a changed Rodnan Skin Score extra than 10 have been randomized to rituximab (375 mg/m2) or placebo for 24 weeks (Ebata et al ., 2021)

Secondly, large-scale observational studies/randomized controlled trials, more sensitive outcome measures, and strict control of confounding factors are needed to draw convincing conclusions to guide the safe and efficient use of intravenous anesthesia in clinical practice

As research in this field continues, unraveling the precise mechanisms governing Th17 cell modulation by the microbiota holds promise for advancing our understanding of autoimmune diseases and informing future therapeutic interventions

The Synergistic Threat of Air Pollution and UV Damage Air pollutants, such as particulate matter (PM), interact with UVR to exacerbate oxidative damage

EClinicalMedicine 18 , 100213 (2020)
