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In a rat model of focal cerebral ischemia, 3-AB reduced lesion volumes and attenuated NMDA-induced neurotransmitter dysregulation 173
This restoration of metabolic cofactor availability enables enhanced function of NAD+-dependent enzymes including sirtuins, poly(ADP-ribose) polymerases, and various deacetylases that regulate cellular metabolism, stress responses, and aging processes
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Copper-GHK increases integrin expression and p63 positivity by keratinocytes
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