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TB-500 has demonstrated similar positive results across various experimental paradigms

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For example, vitamin D induces BDNF release via calcium signaling by upregulating voltage-gated calcium channels, while folate and B vitamins are involved in neuroprotective effects through limiting neurotoxic homocysteine levels, which inhibits neurotrophic signaling [221]

A pH meter from Essex, UK, was used to measure the pH

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