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At the extreme end of this situation, where there is a genetic deficit in carnitine biosynthesis, some nasty stuff happens without carnitine supplementation [1]: Liver damage and dysfunction Brain damage Muscle weakness Lethargy Exercise intolerance Yet, there can also be situations of mild deficiency where these overt signs arent present

One reasonable approach is to regulate the expression of endogenous Apos to inhibit atherosclerosis via reducing the level of endogenous atherogenic Apos or mutating them and urging the synthesis of endogenous anti-atherogenic Apos

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An historical perspective on GABAergic drugs
