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Bromodomain inhibition targeting BPTF in the treatment of melanoma and other solid tumors

Aberrant inflammation and lethality to septic peritonitis in mice lacking STAT3 in macrophages and neutrophils

This reflects an evolving regulatory pathway, not a finding of harm
In 2014, more than 1.9 billion adults (39% globally) were overweight [43] and obesity continues to rise to epidemic proportions

PMID 29298056 30 Hsieh VC, Krane EJ, Morgan PG
