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AKT is a key regulator in the insulin signaling pathway and regulates several downstream proteins, such as the transcription factor FOXO1, glycogen synthase kinase 3 (GSK3) as well as mTOR and Forkhead transcription factors [65, 66]

However, because the metabolism of glutamine produces ammonia as a byproduct, taking excessively large single doses can overwhelm the liver's ability to process the nitrogen, leading to transient nausea, upper GI discomfort, or belching

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We examined the adult fat bodies in treated and untreated animals to see whether similar responses are present in our models

The data were insufficient to allow clear conclusions to be reached