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Transplant Direct (2019) 5:e502

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The dysfunction and downregulation of the two most studied efflux transporters at the BBB, PGP, and BCRP is linked to pathological changes in neurodegenerative diseases, like Alzheimers and Parkinsons diseases [12]

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Nicotinamide adenine dinucleotide phosphate (NADPH) is an important electron donor and functions as a critical ROS scavenger in antioxidant systems

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