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Many protocols follow a 5-days-on, 2-days-off schedule to prevent receptor desensitization

Medications: Some drugs, like proton pump inhibitors and metformin, can block B12 absorption

Glucosinolate-derived isothiocyanates impact mitochondrial function in fungal cells and elicit an oxidative stress response necessary for growth recovery

In cardiac surgery, direct contact between blood and the CPB circuit induces an inflammatory response mediated by cytokines such as interleukin-1 (IL-1), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-) [3, 11]

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