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Likewise, in addition to the mentioned Parkinsons disease models [198,199,200], these were induced by various central causes (e.g., spinal cord compression [170,230], stroke [145], traumatic brain injury [231], neurotoxin cuprizone that mimics multiple sclerosis in rats [232], neuroleptics [199,200], amphetamine [200,233], alcohol acute and chronic intoxication [234], serotonin syndrome [235], and NO-system blockade [200])

For instance, some tripeptides promote fibroblast activity and collagen deposition 59 , 61 - 64 , while others enhance angiogenesis and modulate inflammation to accelerate tissue regeneration 58 , 60 , 65 , 66

Various natural compounds, such as curcumin, piperine, plumbagin, thymol, quercetin, and sinapic acids, have been shown to affect Pseudomonas biofilm formation