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Reported reactions include: Reactive thrombocytosis Hypersensitivity: rash, pruritus, anaphylaxis Headache, paraesthesia, tremor Cardiac arrhythmias secondary to hypokalaemia Nausea, vomiting, diarrhoea Fever, chills, hot flushes, dizziness, malaise Injection site reactions: pain, erythema, pruritus, induration, swelling Acneiform and bullous eruptions Chromaturia (red/orange urine) Overdose Treatment is unlikely to be required

The metabolic acidosis and the 5-oxoprolinuria in these patients are explained by the decreased feedback inhibition of -glutamylcysteine ligase resulting from the lower GSH levels

Microneedling creates temporary micro-channels in the skin, and applying a glycol-containing serum through compromised skin introduces those solvents more directly into tissue than a standard topical application would

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Comprehensive review on collagen extraction from food by-products and waste as a value-added material