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Description
According to Kaplan et al., intra-VTA A 1 R agonism suppresses morphines effects on motor activity and VTA projections neural activation, including Fos immunoreactivity in the nucleus accumbens [80]

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It also supports the release and synthesis of acetylcholine, as well as enhances the release of dopamine from neurons and helps it bind to dopamine receptors

Braz J Biol 82:e267633 [DOI] [PubMed] [Google Scholar] 4.Alghamdi HY, Alrashed AM, Jawhari AM, Abdel-Moneim AS (2022) Neuropsychiatric symptoms in post-Covid-19 long haulers
