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The patients biochemical abnormalities gradually resolved with intravenous fluids, sodium bicarbonate, and discontinuation of acetaminophen

In mammals, the main enzymes responsible for the formation of eicosanoids and docosanoids, namely lipoxygenases (LOX), cyclooxygenases (COX), and cytochrome P450s (CYP), also utilize C18-FAs as substrates

The artificial cerebrospinal fluid used for recordings contained (in mM): 125 NaCl, 25 NaHCO 3 , 25 glucose, 2.5 KCl, 1.25 NaH 2 PO 4 , 2 CaCl 2 , and 1 MgCl 2 , pH 7.3 gassed with 95% O 2 5% CO 2

doi: 10.1158/0008-5472.CAN-19-0274 45 MarigoIBosioESolitoSMesaCFernandezADolcettiLet al