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As such, our current and previous findings highlight the potential therapeutic effect of NHPN-1010 on ribbon synapses 34,40

Gammella, E., Recalcati, S., Rybinska, I., Buratti, P

Cancer 139 (8), 16831695

Patients who follow only some of those elements report variable results, which they then attribute to the device or the serum rather than to the protocol

To overcome this, various techniques such as peptide cyclization, amino acid substitution with D-isomers, PEGylation, and encapsulation in carriers (e.g., nanoparticles, hydrogels) are being explored, though these approaches can increase complexity and production costs
