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Notably, post-mortem studies revealed reduced activity of respiratory chain complexes in a group of ASD children, suggesting that abnormalities, especially in the frontal, temporal and cerebellar areas (Chauhan et al., 2011
Currently there is no established upper limit for B12 due to the low potential for toxicity

Handling: Reconstitution and storage should follow standard laboratory protocols
Clearing 4-HNE or enhancing its detoxification capacity through acetaldehyde dehydrogenase and GSH pathways has shown neuroprotective effects in PD models (88)

doi: 10.1023/A:1018490212481