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But later, they can play a vital anti-inflammatory role to cause a resolution of the pain state. Completely shutting down glial cell activation could lead to bad consequences

A longitudinal laser fluorescence study of white spot lesions in orthodontic patients

Microglia: the metabolic checkpoint The decision of microglia to either support or prune neurons and synapses may be guided by a metabolic checkpoint. We postulate that microglia constantly assess the metabolic fitness of neighboring neurons by sensing specific metabolites released from dysfunctional cells