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In 2018, a Biochemical Pharmacology study reported that membrane-permeable NNMT inhibitors given to obese mice cut white fat mass and body weight and shrank adipocytes [5]
Because cysteine is often the scarcest of the three amino acids needed to make glutathione, NAC acts as a "rate-limiting" precursor
This article was edited by Tracy Vence and Kalee Thompson
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doi: 10.1016/j.freeradbiomed.2016.01.029, 44 Van MalderenS.HehlM.VerstraelenS.BreugelmansR.OeltzschnerG.SwinnenS