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Anti-tumour efficacy was compared to the anti-EGFR antibody cetuximab to exclude any EGFR blockade effects on tumour growth inhibition 25 and determine the ability of a bispecific format to inhibit BRAF -mutated tumours by EGFR-specific T-cell activation

Nevertheless, the authors of the study advocated caution, citing this cohort as the peak age for the development of pneumococcal meningitis

Statements Author contributions YH: Conceptualization, Writingoriginal draft

Moreover, we observed a similar response in phase three compared to phase one, where combining L-citrulline and GSH effectively increased plasma nitrite and NOx concentration in humans compared to placebo

doi: 10.3233/ADR-230172