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It is thought to reduce the production of prostaglandins (chemicals that cause inflammation) in the brain and to lower fever through its action on heat-regulating centers in the brain but the precise mechanism remains unclear

Chin J Behav Med Sci

Nutrients 11:847

Notably, alterations in the binding of AP-1 family members, such as FRA-2 and JUND, were closely linked to increased DNA methylation, suggesting that mutant HTT may disrupt normal transcriptional regulation (212)
doi: 10.3389/fmicb.2023.1207132 131 YangMLuoSYangJChenWHeLLiuDet al
