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PMCID: PMC7281326

76,77,78,79,80 Therefore, changes in the NADP/NADPH ratio may determine the sensitivity of ferroptosis, while ferroptosis-resistant cell lines may have higher basal NADPH levels or lower NADP/NADPH ratios

The optimal dosage and frequency are determined through consultation with healthcare professionals, who consider factors such as the underlying cause of deficiency, individual health status, and response to treatment

[DOI] [PubMed] [Google Scholar] dos Santos A.A., Medina S.V., Sholl-Franco A., de Araujo E.G

Therefore, NASO B12 is highly effective in treating the vitamin B12 deficiency when compared with the oral treatment in type 2 diabetes mellitus patients on metformin therapy and would be a game changer in overcoming the limitations of oral and intramuscular treatment of vitamin B12