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BPC 157 and Parkinsons Disease and Alzheimers Disease Commonly, NO has a well-known dual potential, i.e., neuroprotective potential in some contexts and neurodegeneration if produced excessively or in the wrong context
2018;25:447459.e4

Mori K, Obara Y, Moriya T, et al

To improve solubility, stability, and tissue targeting of these phytochemicals, nanoparticles, liposomes, polymer conjugates, micelles, and phospholipid complexes have been investigated [366, 378]
Changes in the BBB associated with Alzheimer's disease primarily include endothelial abnormalities such as reactive gliosis, mitochondrial damage, alterations in the extracellular matrix, disrupted tight junctions, and both molecular and functional changes in astrocytes
