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( D ) Liver metastatic (PDAC) cell lines stably expressing non-targeting Control, sh Gstt1 or ipCW- Gstt1 in the presence of control shRNA or shRNA targeting FN1 were plated and conditioned media was collected 5 days after dH2O or doxycycline treatment (where indicated)

Inactivation is caused by oxidation of the cluster followed by release of Fe a (which is required to coordinate OH on C 3 position of citrate) and cluster disassembly (Gardner, 1997)

Luchinat, E

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Inhibition of Escherichia coli chromosome replication by rifampicin treatment or during the stringent response is overcome by de novo DnaA protein synthesis