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10.1210/en.2010-0890 50 GermanJ
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Proc Natl Acad Sci 2021
Because H 2 S-induced neurotoxicity may be mediated via enhancement of N -methyl-d-aspartate receptor (NMDAR) activation [64,65,66], we developed a novel hybrid H 2 S-releasing molecule, S-memantine, which is a combination drug of slowly H 2 S-releasing molecule chemically conjugated with memantine which is a moderate NMDAR antagonist and approved for the treatment of Alzheimers disease patients
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