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Furthermore, the mechanisms of their import, including interaction factors and important sequence features, and functions in mitochondria are yet to be elucidated

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5 Division of Hospital Internal Medicine, Department of Medicine, Mayo Clinic, Rochester, MN, USA Correspondence: Rakesh Kumar, Department of Psychiatry and Psychology, Mayo Clinic, 200 First Street SW, Rochester, MN, USA, 55905, Email [email protected] Abstract: Acetyl-l-carnitine (ALC) is increasingly recognized for its potential psychopharmacological mechanism and role in the treatment of mood disorders, particularly major depressive disorder (MDD) and bipolar disorder (BD)

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This unique mechanism of action may be effective in situations where other medications have failed

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One human studies conducted by Vrieze and others demonstrated that FMT transiently increased peripheral insulin sensitivity in patients with metabolic syndrome, which might be linked to elevated rates in the donors gut of pre-production bacteria (Vrieze et al., 2014)

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