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Medicinal plants, an important source of herbal medicine, are gaining more demand with the growing human needs in recent times

It has an asymmetrical shape, and an irregular faintly pigmented border

Metformin is generally described as safe, effective and cheap, but one notable harm associated with its use is vitamin B12 deficiency

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Finally, our structures reveal mechanistic details of MC4R activation/inhibition, and provide important insights into the regulation of the receptor signaling profile which will facilitate the development of tailored anti-obesity drugs.