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Therefore, approaches that can improve the condition and prolong the survival of patients with acute liver failure awaiting a liver transplant would increase the number of potential organ offers for a cadaveric graft, reducing the use of marginal donors and even allowing transplants to be performed in patients currently not receiving a graft offer

Khan emphasizes the difficulty of fixing doses based on body weight in developing children, leading to the prevalent testing and development of drugs primarily for adults, who tend to have more stable weights