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Description
Skin signs that may suggest the dose is high for your body include a widespread rash beyond the injection site, persistent swelling that does not clear between weekly doses, or new hives away from the injection point
PRP is often done as a facial with microneedling or specifically injected under the eyes to combat dark circles
USDA, 2021)

This includes patients with pernicious anemia, a condition where the body cannot absorb B12 from food

Researchers noted that further study is necessary to fully assess the impact of B12 on sleep
